The Anodyne Two was a starship operational during the war between the First Order and the Resistance. It shared its name with the Nebulon-C escort frigate Anodyne, a Resistance starship destroyed by the First Order in an attack on its fleet. When General Lando Calrissian called for allies during the Resistance's battle against the Sith Eternal forces above the planet Exegol, the Anodyne Two joined a fleet to assist in the battle.