Sapani is best known for playing Sembene in the horror drama series Penny Dreadful, and Berber the Moor in the historical drama series The Bastard Executioner. Other roles of note include gang member Nate in Danny Boyle's psychological thriller film Trance, probation officer Tony Morecombe in the first episode of the science fiction series Misfits, and Colonel Manton in the Doctor Who episode "A Good Man Goes to War."