The Imperial Science Bureau, also known as the Imperial Science Corps, was a division of the Sith Empire that was dedicated to research and development of new technology. It held a significant amount of influence in order to achieve its aims through other agencies within the Empire.
During the Cold War, they were responsible for getting the Imperial Diplomatic Service to assign Ambassador Vector Hyllus assigned on Alderaan in order to get him to encounter the Killiks so that they could witness the process that transformed a sentient into a Joiner. This was all part of Project Protean that sought to find means to use alien species to enhance Imperial operatives by means of genetic engineering. In addition, they constructed a device called a Brood Totem that worked to lure Killiks to its position following synchronization and deployed Special Tactics Group 41-Delta on this mission.
Nadrin Tro and a Human female of the bureau's New Thinking Division were sent to the planet Makeb during the Conquest of Makeb. Under Katha Niar, they worked to secure Makeb's isotope-5 deposits for the Sith Empire. At an Imperial hero's command, Nadrin Tro contacted the Science Bureau for help in devising the plan to stabilize Makeb's planet core to buy time for the Empire to extract the isotope-5 within.