Isabet Reau was eager to train the clones in the ways of the Death Watch's ideal Mandalorian. Reau saw the transmission of Mandalorian culture and tactics to the clone troopers under her instruction as a way of regaining her people's galactic influence and renown. Along with her boyfriend, Dred Priest, she hosted a fight club in secret on Kamino. When clones started dying, Jango Fett put an end to it by badly injuring Priest.
The Ba'jurne Kyr'tsad Mando'ad, a manifesto of the Death Watch Mandalorian splinter group, was supposedly written by the movement's leader, Tor Vizsla—although in one of his notes the Death Watch's opponent Jango Fett doubted its authenticity and suggested that Dred Priest or Isabet Reau wrote the manifesto—and was eventually included in the book The Bounty Hunter Code by Jango's son, the bounty hunter Boba Fett.
Isabet Reau in full armor.
In 18 BBY, a year after the Galactic Republic was transformed into the Galactic Empire, Priest and Reau were stationed on Mandalore where they were seen aiding the Imperial garrison there. They were soon noticed by Kal Skirata and his clan. After noticing the Death Watch insignia on their armor, an enraged Mij Gilamar attacked Priest above the river outside Keldabe and severed his femoral artery. Knowing Reau would be looking for Priest, Gilamar tossed his body into the river, hoping to delay her wrath.
Reau was described as insane by Mij Gilamar and said to be worse than Priest by wanting the old days of a Mandalorian empire to be reborn.
Reau wore yellow-and-gray armor with a yellow kama.
Isabet Reau was created for an exclusive Entertainment Earth 14 action figure pack. This figure shares some parts with the Rav Bralor figure, but features a new head, belt, rocket pack, and kama with a completely unique paint job. The featured picture is of a prototype. The final figure is colored nearly identical to Mirta Gev's gear. This was likely intentional, considering the colors of the Dred Priest figure (also part of the EE set) which closely mimic that of Mirta's spouse Ghes Orade.