Kelly is an American comic-book writer, editor, and English-language adapter of manga. She has worked for several American comic companies including Image Comics, Dark Horse Comics, DC Comics, and Marvel Comics. Some of DeConnick's most recent works include the Pretty Deadly and Bitch Planet comics, and Carol Danvers' rebranding as Captain Marvel. Kelly is also the wife of critically acclaimed comic writer Matt Fraction, and the two have a son named Henry and a daughter named Tallulah.