In the year 3627 BBY, during the third Galactic War, the Krakana stopped at Mek-Sha along with the rest of the Twenty-Ninth Fleet on their way to Corellia to aid in the defense of the Meridian Complex. However, while on Mek-Sha, it was targeted by the Sith Empire, which aimed to destroy it and the fleet so that it could not be able to continue on to Corellia.
However, the Empire's plans to destroy the ship were stopped by the Alliance Commander, who battled through the Empire's forces, including Lord Tarnux and Major Anri, and saved the fleet as well as the Krakana.
Following this, the Krakana arrived to defend against the attack on the Meridian Complex, and helped to successfully fight off the Imperial Fleets.
The Krakana appears alongside the Twenty-Ninth Fleet during the Onslaught expansion for the game Star Wars: The Old Republic, and is mentioned by name in a codex entry for Vice Admiral Narlock. If the player character is a Republic Loyalist or an Imperial Saboteur, they will save the Krakana from being destroyed by the Empire. However, if the player character is an Imperial Loyalist or a Republic Saboteur, they will successfully destroy the Krakana and prevent it from being present during the defense of the Meridian Complex.