Omega Red was a deadly Sith toxin created by Darth Maladi around the year 138 ABY, based on the New Republic bio weapon Alpha Red. Unlike the original strain, which was designed to target Yuuzhan Vong, Omega Red was capable of killing any kind of species. She offered to reveal its secrets to the exiled Emperor Roan Fel in exchange for safe haven and Cade Skywalker's life. Roan Fel agreed to the deal in hopes of wiping out his rival, Darth Krayt, but it turned out that the Sith were immune to the toxin by design as a trick by Maladi and Krayt to wipe out Coruscant. It was almost utilized by Fel until Antares Draco killed him to prevent it from being used.