The office belonging to Padmé could be found right above a platform for landing within the Republic Executive Building. She utilized this space for her official duties, such as creating new laws and putting her signature on official papers.

Her office was frequently used by Anakin Skywalker and Padmé Amidala as a clandestine location to rendezvous during the day, so that their hidden marriage would not be exposed. They were both present in the office shortly before Cad Bane took a collection of Senators as hostages, with Amidala among them. However, their intimate moment was disrupted by the arrival of Bail Organa, which resulted in Skywalker concealing himself beneath the desk.
Even with the planet being actively assaulted during the Battle of Coruscant, Padmé made her way to her office to retrieve essential documents.