The series covers the story of the Yuuzhan Vong War by focusing on the Galfridian family, the royal family from the peaceful world of Artorias, one of the first to fall under the Yuuzhan Vong invasion, which resulted in its entire population being evacuated, enslaved, or killed. A young man named Finn Galfridian is set on the Jedi path by Luke Skywalker, while things for his sister Kaye Galfridian and the rest of the family "don't go so well." Many characters from The New Jedi Order series, such as Luke Skywalker, Jaina Solo and Jacen Solo are also featured in the series.
Refugees and Rescues take place between the novels Vector Prime and Onslaught, and Revelations takes place between Onslaught and Ruin.
Colin Wilson, who had previously drawn Star Wars comics for Dark Horse, was working with Australian writer Tom Taylor on a comic-book adaptation of his play The Example and suggested that Wilson contact Dark Horse editor Randy Stradley. Taylor was quickly accepted into the Dark Horse creative team and worked for some time on an unidentified Star Wars project which eventually got canceled before going on to Invasion. The series was first announced by Dark Horse Comics on February 7, 2009 during the New York Comic Con. The addition of another monthly series to an already significant number of Star Wars comic-book series was possible due to the success of the Star Wars: Vector crossover published by Dark Horse in 2008.