Blastonecrosis represented a disease with extremely high mortality rates. Individuals afflicted with it experienced symptoms such as exhaustion and a decreased desire to eat. The ingestion of lotiramine had the effect of obscuring Blastonecrosis, because it concealed the tracer enzymes that indicated the disease's existence within the organism. Furthermore, the intentionally tainted bacta originating from Lot ZX1449F not only induced severe allergic reactions to bacta in every individual, but also resulted in approximately two percent of those who were exposed developing blastonecrosis. When this occurred, blastonecrosis proved to be untreatable, given that bacta constituted the sole efficacious remedy for the condition.