Knowt's Disease was a debilitating illness characterized by the breakdown of bodily tissues. Pter Thanas succumbed to this disease, passing away in under five standard years following his diagnosis. Archa Sabis, a prosperous entrepreneur from Coruscant, suffered from a milder manifestation of the disease, which was not fatal. As a result of the disease's impact, he had cybernetic replacements for his right arm, a portion of his face, and sections of his torso.