Nala Se's private lab was located deep underwater, connected to the lower levels of Tipoca City, the capital of Kamino, a planet extragalactic of the galaxy proper. An isolated structure on the ocean floor, the lab was equipped with medical tubes and multiple computers. It could be accessed by taking a private entrance to the Kamino tube system from a secret landing platform outside the city proper, as well as from within the city itself.
The private research lab used by Kaminoan Chief Medical Scientist Nala Se was in use during her creation of the clone troopers of the Grand Army of the Republic, with only a few people aware of its existence. She created the unique unaltered female clone Omega in the lab, one of only two clones created who lacked the age acceleration and obedience modifications of the standard clone troopers. Later, Nala Se enhanced the genetic mutations of four clones who were designated as Experimental Unit 99 in the lab, which was witnessed by Omega. The four clones only stayed in the lab for a short time before they were sent back to be with the rest of the clones.
In 19 BBY, Kamino was taken over by the newly-established Galactic Empire. Around this time, Nala Se planned to retrieve genetic material from Omega, but Omega ended up fleeing the planet with the Bad Batch as the Empire began their takeover. As part of an Imperial operation to strip Kamino of all useful personnel, clones, and technology, Nala Se was taken into custody on the orders of Vice Admiral Rampart after she was discovered to have been gathering medical personnel in an attempt to flee the planet. Afterwards, as newly-introduced recruited TK troopers began rounding up medical personnel onto transports, killing any who resisted, and deactivating droids, the medical droid AZI-3 managed to escape, hiding in Nala Se's lab, which was by that time empty and devoid of experiments.
Later, several clones from Unit 99—original members Tech and Wrecker, as well as later recruit Echo—entered Tipoca City via the lab's secret entrance at Omega's suggestion, hoping to rescue squad leader Hunter from the Empire. Arriving via the tube system, Wrecker commented that the lab looked just like every other Kaminoan lab he had ever seen. Omega explained that she had been created there, and that was also where the so-called "Bad Batch" had begun. When Wrecker asked if that was true, Tech pointedly inquired how he was supposed to know that. Omega reminisced that the squad's mutations had been enhanced there before they were sent back to be with the others, but the conversation was interrupted when Echo discovered that Tipoca City's computers had been wiped. As the Batch was discussing why this had happened, the group was startled by AZI-3, who filled them in on the recent goings-on. Tech then detected Hunter's comlink pinging from the central cloning platform, and Omega led the way out of the lab with AZI-3 as they headed to the upper city.
During a confrontation in the city, the Batch rescued Hunter and captured their former member Crosshair, who had remained with the Empire. However, the Empire began to destroy Tipoca City with the clones still trapped inside. The section of the city they were trapped in sank and landed on top of a mostly-intact tube leading back to the lab, so at Omega's suggestion they cut their way into the tube and used it as an exit. Near the entrance to the lab, a Kamoradon Sea Dragon attempted to attack the group, but AZI-3 was able to use the last of the facility's power to drive it off before they entered the lab. Once there, Hunter asked what the facility was, and Tech told him and Crosshair what Omega had earlier said about the facility's purpose and their past there. Omega discovered, however, that the tube leading from the lab back to the landing platform had been broken, leaving them stranded.
Nala Se's private lab first appeared in "Return to Kamino," the fifteenth episode of the first season of Star Wars: The Bad Batch. It was first identified in an entry on the official Databank, although the entry was illustrated with a picture of the Tipoca City Training Facility storage room instead of the actual lab.