Between the years 3681 and 3653 BBY, within the timeline of the Great Galactic War that pitted the re-established Sith Empire against the Galactic Republic, the Twi'lek slave named Leontyne Saresh spearheaded a rebellion with other enslaved people against the Empire's presence on the world of Edusa. The consequence of this uprising was the liberation of numerous slaves, and Saresh subsequently became a dedicated adversary of both the Empire and the practice of slavery within the Galactic Senate.
The initial reference to the Edusa revolt appeared within the biographical information for Leontyne Saresh, found in the 2012 reference book Star Wars: The Old Republic Encyclopedia.