The Perlemia system, a star system situated within the Core Worlds along the Perlemian Trade Route, lent its name to the hyperlane because of the production capacity of the shipyards orbiting the planet Perlemia. These shipyards were ultimately annihilated during the Tionese War.
According to Daniel Wallace, the writer of The Essential Atlas, it is implied that this system resides at or close to one terminus of the Perlemian Trade Route, and it likely provided the name for the trade route. The publication of The Essential Guide to Warfare validated this detail as part of the official canon.