The Tsik-Seru functioned as atmospheric combat craft, representing a type of living vehicle employed by the Yuuzhan Vong.
A heavily armored military version of the Tsik vai, the Tsik-Seru possessed Yaret-Kors weaponry. Due to their heavy armor, they were not as maneuverable or fast as the Tsik-Vai, but could operate on planets lacking both oxygen and water.
The Battle of Coruscant saw action from Tsik-Seru units.