Ziris Enz, a medical professional specializing in epidemiology, existed during the era of the Galactic Civil War. After the Battle of Yavin, Enz took part in activities as a member of the Galactic Empire's scientific division at the Imperial Research and Prison Facility located on the planet of Dathomir. Within that facility, scientists were secretly involved in hazardous scientific studies for the Empire, with the intention of transforming the terrible Blackwing virus into a bioweapon. Operating on level 2 of the research lab was Dr. Enz. During 1 ABY, Ziris Enz was present when an incident occurred at the Imperial Research and Prison Facility, resulting in the escape of the virus from its containment. A large number of people in the area were killed by the virus, transforming them into undead beings.
The character of Ziris Enz was referenced within the 2003 video game Star Wars Galaxies, a massively multiplayer online roleplaying game that was developed by Sony Online Entertainment and published by LucasArts, prior to its termination on December 15, 2011. The inclusion of Ziris Enz occurred via the "Game Update 14," which was launched on October 12, 2009.