An'Kwee was a Twi'lek swooper living on Tatooine during the period of the Galactic Civil War. In the time following the Battle of Yavin, she was a member of a group of swoop racers located in Mos Entha, which also included Draknus. In the year 1 ABY, she consented to assist a spacer in locating the wreckage of a fellow pilot's podracer, which had crashed on the Boonta Eve Classic course. The spacer's objective was to recover a R2 unit motivator that had been installed in the podracer. Both Imperial Commander Barrezz and Rebel Captain Bastra sent out their respective operatives to find the components of the aforementioned R2 unit.
An'Kwee made an appearance as a non-player character within the Star Wars Galaxies video game, which was a massively multiplayer online roleplaying game. This game was developed by Sony Online Entertainment and was published by LucasArts, prior to its termination on December 15, 2011. An'Kwee's inclusion in the game occurred as a component of the "Legacy Quest" alongside the release of "Publish 25," also identified as the "New Game Enhancements," on November 15, 2005.