The Biox Detour, a hyperspace trade route, was identified by the former pirate Queen Maz Kanata in a map included in the book that later became the Smuggler's Guide. She considered it a "real" route for smugglers, distinct from official channels. This route linked Takodana, a planet situated in the Mid Rim, to the Ring of Kafrene, a mining colony located in the Expansion Region. The Ring of Kafrene then served as a connection point to the Rimma Trade Route. From there, the route extended to Malastare, another planet in the Mid Rim, functioning as a junction with the Hydian Way.
Daniel Wallace initially introduced the Biox Detour in Star Wars: Smuggler's Guide, a reference book published in 2018.