The Gestrex system existed within the Calaron sector, which itself was located in the Slice region of the Outer Rim Territories. This system's connection to both the Kegan and Norval systems was facilitated by the hyperlane called the Triellus Trade Route.
Within the Gestrex system was the planet Gestrex III, which served as the location for a base belonging to the Galactic Empire's Navy during the Galactic Civil War. Sometime between the years of 2 BBY and 1 BBY, a Rebel Alliance commando unit destroyed the installation. Following this event, the base was left vacant.
The initial mention of the Gestrex system occurred in the 2009 publication The Essential Atlas. This reference book, written by Daniel Wallace and Jason Fry, situated the system within grid coordinate T-9.