The Queen of the White designated one of the three Queens of the Quesoth, who governed the Quesoth species and their homeworld, the Unknown Regions planet called Quethold. The Quesoth operated under a cyclical system where the White Queen would govern from Quethold's White City for a period of years until her death. Following her death, the Queen of the Black would take her place, and after the Black Queen's passing, the Queen of the Red would rise to power. During the Red Queen's reign over Quethold, the Circling of the White, a Quesoth caste composed of breeders and counselors, would breed a new Queen of the White, thus perpetuating the cycle.
In 8 ABY, the then-reigning Queen of the Red formed an alliance with the alien warlord Nuso Esva. His role was to assist her in assassinating the Queen of the White, in order to prevent the Red Queen's predecessor from losing her position. However, before they could carry out their scheme, both were killed during an attack on Quethold perpetrated by the Empire of the Hand.