The Western Dune Sea constituted a portion of the Dune Sea found on the planet Tatooine. While living as a recluse on Tatooine, Obi-Wan Kenobi made his home in a residence situated at the border of the Western Dune Sea.
During the year 0 BBY, the escape pod containing C-3PO and R2-D2 made its landing within this region.
According to information presented in Star Wars: Absolutely Everything You Need to Know, the Mos Espa Grand Arena was said to be positioned along the edge of the Western Dune Sea. Conversely, Ultimate Star Wars explicitly points out that Mos Espa, along with its surrounding areas, was situated where the Xelric Draw met with the Northern Dune Sea.