DP-6 Guard Droid functioned as a security droid for the reconstituted Sith Empire, seeing action throughout the Galactic War against the forces of the Galactic Republic. It was present at the Battle of Corellia in 3640 BBY, where it served as a guardian for Darth Thanaton's headquarters, situated within the Museum of Corellian Industry; its operational existence came to an end when Kallig, Thanaton's adversary, eliminated it.
The DP-6 Guard Droid is featured in the 2011 massively multiplayer online role-playing video game Star Wars: The Old Republic, developed by BioWare, specifically during the Sith Inquisitor storyline on the planet of Corellia.