The Nexus served as a trading station positioned in orbit above the planet of Quarmendy. During the initial stages of the Clone Wars, Wat Tambor led the Confederacy of Independent Systems in their occupation of the Nexus. The Republic launched a mission in 22 BBY with the aim of capturing the planet Quarmendy, with the Nexus as their objective. As part of that mission, and after being surrounded by Jedi Master Plo Koon's Wolfpack, Tambor annihilated the Nexus.