Khandra, a Jedi of human descent, identified as female and dedicated her life to the Galactic Republic during its twilight years. As the Clone Wars drew to a close, Darth Sidious issued Order 66, prompting Khandra to seek refuge with three allies – Mususiel, Zubain Ankonori, and Nuhj – within a secluded Jedi shrine located on the planet Anoat. However, their sanctuary was eventually compromised, leading the Galactic Empire to send an Inquisitor to eliminate them. To facilitate the others' escape, Mususiel bravely stayed behind on Anoat, acting as a diversion.
On Mataou, Ankonori took on the role of drawing their pursuer away, allowing Khandra and Nuhj to escape to Burnin Konn. With the Inquisitor having killed Mususiel and Ankonori, Khandra's connection to the Jedi Order began to erode as she was relegated to a life of concealment and foraging for sustenance. Sometime later, the Inquisitor reappeared, resulting in a fatal confrontation at a chromium mine near Wickridge where both Khandra and Nuhj met their end. Their possessions, which included a broken lightsaber, were subsequently locked away in an Imperial storage facility on Nar Hypa.