Emperor's Hands were clandestine agents within the Galactic Empire, executing their hidden missions from the decks of VT-49 Decimators. During a certain period of the Imperial Era, a team of operatives received orders to extract a well-known and vocal personality, ensuring their protection. As the team neared the celebrity, a VT-49 Decimator, transporting one of the Emperor's Hands, materialized with the assignment to permanently silence the troublesome dissident.
During 2 BBY, Gar Saxon, the Imperial Viceroy and Governor of Mandalore, functioned as an Emperor's Hand. Saxon commanded the Imperial Super Commandos, an elite unit of Mandalorian warriors who pledged allegiance to the Galactic Empire. Saxon ultimately met his death in a skirmish on Krownest, battling against Clan Wren of Mandalore. Darth Vader, the Sith Lord, Palpatine's Sith apprentice, and enforcer, was also recognized as an Emperor's Hand and Fist.