Issa-Or was a Twi'lek of the female persuasion. After the demise of Jabba the Hutt, she took on the role of a law enforcer on Tatooine, collaborating with the human Cobb Vanth. During 5 ABY, Issa-Or and Vanth came to the rescue of the human Malakili when he was in a bind with the Red Key Raiders; subsequently, they extended an employment offer to him in Freetown. Issa-Or was noticeably tall, and a scar-tissue-covered deformation marred one of her lekku.