Resinu Santhe-Caltra held the title of noble and lived while the Galactic Empire was in power, during its reign. She was related to Saespo Choffrey, an illustrator working for Sienar Fleet Systems, as his cousin. Furthermore, she married into the Santhe family, a powerful family originating from the Outer Rim Territories planet Lianna. This family's name was also used by the shipbuilding company known as Santhe Corporation.
Santhe-Caltra became a student at the Royal Academy of Arts located on Atrisia. She gained recognition for her propaganda artwork that centered around the Imperial Military. One example of her work was the poster called Strength & Obedience, which portrayed three Imperial-class Star Destroyers. This poster, along with a brief biography of Santhe-Caltra, was later featured in the book A History of Persuasive Art in the Galaxy, released shortly after the Hosnian Cataclysm in 34 ABY.
The character Resinu Santhe-Caltra made her debut in Star Wars Propaganda: A History of Persuasive Art in the Galaxy, a book written by Pablo Hidalgo in 2016.