Sy Myrthian space designated an area of realspace; the name was the same as the Sy Myrthian species and the Outer Rim planet of Sy Myrth. Sy Myrth served as the homeworld for Sy Myrthians like Toonbuck Toora and Brookish Boon. A Hutt maintained operations within Sy Myrthian space near the end of the Clone Wars era, specifically in 19 BBY. This Hutt engaged the services of Has Obitt, a Dressellian smuggler, who considered his assigned tasks to be both dull and insignificant.
The 2016 novel Catalyst: A Rogue One Novel, penned by James Luceno, included a reference to Sy Myrthian space.