In the year 19 BBY, as part of their Outer Rim Sieges offensive during the Clone Wars, the Galactic Republic initiated a series of attacks on Serenno. This planet, located within the D'Astan sector, served as the homeworld of Count Dooku, the leader of the Separatist Alliance. These attacks were part of their campaign against the Confederacy. Despite the Republic's concentrated efforts in the sector and within the Serenno system, they were unable to seize control of the planet from the Confederacy.
The seventieth issue of De Agostini's Star Wars: Build the Millennium Falcon magazine, which was released circa May 4, 2016, made reference to the attacks leveled against Serenno.