Battlecruiser 19 served as the callsign for a Munificent-class star frigate within the Confederacy of Independent Systems' naval forces during the Clone Wars. This vessel participated in the Confederacy's blockade of the planet Ryloth during the Battle of Ryloth in 21 BBY, among other frigates. Captain Mar Tuuk, a Neimoidian, commanded the frigate, positioning it in anticipation of an assault by Galactic Republic forces. When a Republic task force under the leadership of Jedi General Anakin Skywalker arrived, Tuuk instructed Battlecruiser 19 and three additional Munificents, including Battlecruiser 17, to engage in the Ryloth system, compelling the Republic to withdraw.
Skywalker's forces later returned to the system, launching a second attack against the blockade. In this renewed assault, Ahsoka Tano, Skywalker's Padawan, led the starfighters of Blue Squadron against the Separatist fleet following the destruction of Tuuk's command ship. Consequently, BTL-B Y-wing starfighter/bombers bombarded and destroyed Battlecruiser 19 and the other Munificents, which enabled the Republic to progress further in their campaign to liberate Ryloth.
Battlecruiser 19, identified by its callsign, was a Munificent-class star frigate measuring 825 meters in length, 426 meters in width, and 243 meters in height. It was propelled by seven ion drive thrusters located at its stern and featured a hyperdrive generator, along with two long-range hyperwave transceiver masts. Its armament consisted of two heavy turbolaser cannons at the prow, two long-range heavy ion cannons, and thirty-four light turbolaser cannons distributed evenly with seventeen on each the port and starboard sides. The emblem of the Confederacy of Independent Systems was prominently displayed on both the port and starboard sides of the frigate's hull.

During the Clone Wars, which pitted the Galactic Republic against the Confederacy of Independent Systems, the Confederate droid armies invaded the planet of Ryloth in 22 BBY, establishing an orbital blockade. This blockade, led by a single Lucrehulk-class Battleship and supported by six Munificent-class star frigates, including Battlecruiser 19, was under the command of Neimoidian Separatist Captain Mar Tuuk.
Following the Confederacy's seizure and blockade of Ryloth, Tuuk's fleet faced a challenge from a Republic task force in 21 BBY. This force, composed of three Venator-class Star Destroyers and led by Jedi General Anakin Skywalker, engaged the Separatist forces. During the ensuing conflict, V-19 Torrent starfighters from the Republic's Blue Squadron, under the direction of Jedi Commander Ahsoka Tano, Skywalker's Padawan, initiated their attack run on Tuuk's Lucrehulk after dogfighting with Vulture-class droid starfighters. In response, the Neimoidian commander directed Battlecruiser 19, Battlecruiser 17, and two other Munificents, which had been strategically positioned in anticipation of a Republic assault, to join the battle within the Ryloth system.
As Battlecruiser 19 and the other frigates emerged from hyperspace and took up their designated attack positions, the Republic forces were caught off guard, resulting in significant damage to Skywalker's Venators. During their forced retreat, the Venator-class Star Destroyer Redeemer was destroyed by the reinforced blockade, with Battlecruiser 19 playing a key role.

Despite the Republic's initial withdrawal, Battlecruiser 19 and the other three frigates remained in the system alongside the blockade, rather than returning to their ambush positions. However, the Republic task force re-engaged the blockade, leading to the destruction of the Separatist flagship. The heavily damaged Venator-class Star Destroyer Defender was piloted by Skywalker and crashed into the command ship. With the Lucrehulk destroyed, the remaining Venator, the Resolute, entered the system and angled its ventral hull towards the Separatist frigates as part of Tano's Marg Sabl tactic.
With the Resolute strategically positioned, Tano directed a second starfighter squadron against the blockade. Meanwhile, the OOM command battle droids on the six frigates questioned their orders following the destruction of their command ship. One of the droid commanders ordered the blockade to open fire on the Resolute. However, during this barrage of turbolaser fire, the Republic squadron's BTL-B Y-wing starfighter/bombers attacked and destroyed the six Munificents, including Battlecruiser 19. Amidst the destruction, Techno Union Foreman Wat Tambor declared the blockade's failure after receiving information from one of the droid commanders. With the blockade eliminated, a Republic invasion fleet led by Jedi Generals Mace Windu and Obi-Wan Kenobi arrived in the system and landed on the planet, advancing the Republic's campaign to liberate Ryloth from Separatist control.
During the assault on the Confederacy's blockade over Ryloth, an OOM command battle droid was in command of Battlecruiser 19. Following the loss of their command ship in the Republic's second attack, the droid commander consulted with the OOM command battle droids of the five other Munificents to determine who was in charge. Unable to establish a clear leader, all six droid commanders agreed to attack the Resolute after its arrival.
Battlecruiser 19 made its debut in "Storm Over Ryloth," which was the nineteenth episode of the first season of the Star Wars: The Clone Wars animated series. It was originally broadcast on February 27, 2009.