Pill droids, utilized by the Galactic Republic in the High Republic Era, were a type of rescue droid. These compact, cylinder-shaped machines were uncomplicated but efficient agents that employed their diverse toolsets to provide aid during perilous medical crises. In 232 BBY, a year that saw the Hetzal system devastated by the Great Hyperspace Disaster, wreckage from the freighter Legacy Run violently dropped out of hyperspace, setting itself on a crash course for the various inhabited locations within the system. Captain Finial Bright of the Republic Defense Coalition deployed one pill droid during a rescue mission at Solar Array 22-X to collect survivors from the destroyed space station.
Pill droids also saw service on the Panacea, a Salvation-class Republic medical frigate that provided care to those affected by both the Disaster and the resulting Emergences. Sometime later, Keven Tarr, a resident of Hetzalian, engineered an elaborate array comprised of navidroids to predict the future points of entry for Legacy Run fragments. Due to the substantial heat generated by the system, Tarr tasked pill droids with applying suppressor foam to the device in order to prevent its self-destruction.